Location History:
- Berwyn, IL (US) (2001)
- Bexley, OH (US) (2009 - 2023)
Company Filing History:
5 out of 106 
4 out of 1,507 
1 out of 1,935 
Years Active: 2001-2025
Title: Mark Edward Peeples: Innovator in Viral Research
Introduction
Mark Edward Peeples is a prominent inventor based in Bexley, Ohio. He has made significant contributions to the field of viral research, particularly in the development of immunogenic compositions and recombinant vectors. With a total of 9 patents, his work has advanced the understanding and treatment of viral infections.
Latest Patents
One of his latest patents focuses on recombinant vectors encoding Zika virus protein subunits. This invention provides compositions, methods, and uses for recombinant vectors that encode Zika virus (ZIKV) protein subunits. The patent includes embodiments that offer recombinant vectors encoding ZIKV nonstructural protein 1 (NS1), as well as ZIKV envelope (E) protein and premembrane (prM) protein. Additionally, it describes expression cassettes that can be incorporated into vectors to produce recombinant vectors, along with immunogenic compositions aimed at inducing an immune response against ZIKV.
Another significant patent involves respiratory syncytial virus (RSV) with altered NS1 protein function. This invention provides methods and compositions for RSV that include a mutated NS1 protein. The mutation allows for the uncoupling of the NS1 protein's replication and type I interferon antagonist functions. This innovation aims to produce virions that can induce a strong, long-lasting innate immune response while maintaining their ability to replicate in vitro.
Career Highlights
Mark Edward Peeples has worked at notable institutions, including the Research Institute at Nationwide Children's Hospital and the Ohio State Innovation Foundation. His research has been pivotal in the development of vaccines and immunogenic compositions that target viral infections.
Collaborations
Throughout his career, Peeples has collaborated with esteemed colleagues such as Jianrong Li and Paul D Olivo. These partnerships have contributed to the advancement of his research and the successful development of his patents.
Conclusion
Mark Edward Peeples is a distinguished inventor whose work in viral research has led to significant advancements in immunogenic compositions and recombinant vectors. His contributions continue to impact the field and offer hope for effective treatments against viral infections.