Location History:
- Winchester, MA (US) (2009)
- Cambridge, MA (US) (1999 - 2010)
Company Filing History:
Years Active: 1999-2010
Title: The Innovative Contributions of Mark Andrew Fleming
Introduction
Mark Andrew Fleming, an accomplished inventor based in Cambridge, MA, has made significant strides in the field of biochemistry through his work. With a remarkable portfolio of six patents, he has contributed to advancements that enhance our understanding of protein structures and their interactions.
Latest Patents
Among his latest patents is the groundbreaking work on the "Crystal structure of Rho-kinase I kinase domain complexes and binding pockets thereof." This invention focuses on the human Rho-kinase I (ROCK I), its binding pockets, and the development of computer systems capable of storing and utilizing structural coordinates for research. His work allows for the identification and design of compounds, including inhibitors, that can effectively interact with the ROCK I protein.
Another innovative patent, "Crystals of inosine monophosphate dehydrogenase/oxidized inosine monophosphate thiomidate intermediate/mycophenolic acid," deals with data storage mediums that visualize the binding pockets of IMPDH on computer screens. This invention aids in solving the structures of homologous proteins and assists in compound design, including pharmaceutical compositions aimed at inhibiting IMPDH.
Career Highlights
Mark Andrew Fleming has established a prominent career at Vertex Pharmaceuticals, an influential company in the biotechnology sector. His work at Vertex is characterized by a focus on developing novel therapeutic approaches through innovative research and experimentation.
Collaborations
Throughout his career, Fleming has collaborated with esteemed colleagues, including Keith P. Wilson and Michael D. Sintchak. These partnerships have allowed him to leverage collective expertise and knowledge, further enhancing the impact of his inventions in scientific research.
Conclusion
In summary, Mark Andrew Fleming stands out as an inventive force in the field of biochemistry. His six patents reflect not only his expertise but also his commitment to pushing the boundaries of scientific discovery. Through his work at Vertex Pharmaceuticals and collaborations with leading scientists, Fleming continues to contribute meaningfully to advancements that have the potential to reshape therapeutic interventions.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.