This inventor holds 6 USPTO granted patents and 2 published patent applications. Top assignees: Beckman Research Institute, City of Hope, University of California. Active years: 2007-2017.
Company Filing History:
6 out of 692 
2 out of 15,964 
Years Active: 2007-2017
Title: Mark A Sherman: Innovator in Antibody Fragment Technology
Introduction
Mark A Sherman is a notable inventor based in Pasadena, CA (US). He has made significant contributions to the field of biotechnology, particularly in the development of antibody fragments. With a total of 6 patents, his work has advanced the understanding and application of recombinant antibody technology.
Latest Patents
One of his latest patents is titled "Covalent disulfide-linked diabodies and uses thereof." This invention provides recombinant antibody fragments that include a variable domain modified by the addition of a tail sequence to its C-terminal end. The tail sequence comprises a terminal cysteine residue and an amino acid spacer, which does not substantially affect the fragment's target-binding affinity. The invention also includes pharmaceutical compositions comprising these antibody fragments and a pharmaceutically acceptable carrier. Furthermore, it outlines methods for delivering agents to cells of interest in a subject using the fragments as delivery vehicles. Additionally, the invention provides compositions for the in vitro detection and measurement of target molecules that bind to the fragments, along with methods for determining the presence or amount of such targets in a biological sample.
Career Highlights
Throughout his career, Mark A Sherman has worked with esteemed organizations such as City of Hope and the University of California. His innovative work has positioned him as a key figure in the biotechnology sector, contributing to advancements that have practical applications in medicine and research.
Collaborations
Mark has collaborated with notable colleagues, including Anna M Wu and John E Shively. These partnerships have fostered a collaborative environment that enhances the development of innovative solutions in the field of antibody technology.
Conclusion
Mark A Sherman is a distinguished inventor whose work in antibody fragment technology has led to significant advancements in biotechnology. His contributions continue to impact the field, paving the way for future innovations.