Mario Amacker

Title: Innovations of Mario Amacker: A Pioneer in Oral Vaccine Development

Introduction

Mario Amacker, an accomplished inventor based in Schmitten, Switzerland, has made significant strides in the field of vaccine development. With a portfolio of four patents to his name, Mario's contributions have paved the way for advancements in oral vaccine dosage forms, particularly through his innovative use of virosomes.

Latest Patents

Among his latest patents, Mario has focused on an "Oral dispersible vaccine comprising virosomes." This groundbreaking work is directed to oral vaccine dosage forms and the processes for producing them. The patent highlights the use of lipid-based vesicles, such as virosomes and liposomes, that harbor an immunogenic amount of at least one vaccinal target molecule, with or without adjuvant. Mario and his team discovered an effective combination of the composition of liquid virosome concentrates, the formulation of the solid dosage form base matrix, and optimal manufacturing conditions. This innovation resulted in a freeze-dried sublingual dosage form that exhibits physical robustness, particle, and antigen integrity, as well as stability.

Career Highlights

Throughout his career, Mario has worked with several notable companies in the biotech industry. His experience includes roles at Pevion Biotech AG and Catalent UK Swindon Zydis Limited, where he has applied his expertise to enhance vaccine delivery systems. His work in these organizations has transformed how oral vaccines are formulated and produced.

Collaborations

Mario is known for his collaborative spirit, having worked alongside distinguished colleagues in the field. Notably, he has partnered with Rinaldo Zurbriggen and Andreas Kammer, leveraging their combined knowledge and skills to drive forward the innovative projects associated with oral vaccine technologies.

Conclusion

In summary, Mario Amacker stands as a visionary inventor whose work in the development of oral vaccines using virosomes has the potential to revolutionize immunization methods. With his extensive patent portfolio and impactful collaborations, he continues to contribute meaningfully to the field of vaccine research and development.