This inventor holds 8 USPTO granted patents and 5 published patent applications, plus 2 CIPO patents and 5 EPO patents. Top assignee: Regeneron Pharmaceuticals, Inc.. Active years: 2023-2025.
Company Filing History:
Years Active: 2023-2025
Title: Marine Prissette: Innovator in Tauopathy Research
Introduction
Marine Prissette is a prominent inventor based in Brooklyn, NY, known for her significant contributions to the field of genetic research and tauopathy. With a total of eight patents to her name, she has made remarkable strides in understanding and addressing tau-related diseases.
Latest Patents
Her latest patents include a CRISPR/Cas screening platform designed to identify genetic modifiers of tau seeding or aggregation. This innovative work features Cas-protein-ready tau biosensor cells and CRISPR/Cas synergistic activation mediator (SAM)-ready tau biosensor cells. Additionally, she has developed methods for making and using these cells to screen for genetic modifiers of tau seeding or aggregation. Her research also provides reagents and methods for sensitizing these cells to tau seeding activity or tau aggregation. Notably, she has identified models of tauopathy, including BANF1, PPP2CA, and ANKLE2, as genes that promote tau aggregation when disrupted. Improved tauopathy models, such as cells, tissues, or animals with mutations in or inhibition of expression of these genes, have also been developed. Furthermore, she has outlined methods for using these improved tauopathy models to assess therapeutic candidates for tauopathy treatment.
Career Highlights
Marine Prissette currently works at Regeneron Pharmaceuticals, Inc., where she continues to push the boundaries of genetic research. Her work has been instrumental in advancing the understanding of tauopathies and developing potential therapeutic strategies.
Collaborations
She collaborates with notable colleagues, including Brian Zambrowicz and Matthew Koss, who contribute to her innovative research efforts.
Conclusion
Marine Prissette's work in the field of tauopathy research exemplifies her dedication to advancing scientific knowledge and developing new therapeutic approaches. Her contributions are paving the way for future innovations in the treatment of tau-related diseases.