Location History:
- McLean, VA (US) (2018)
- Seattle, WA (US) (2019 - 2024)
Company Filing History:
9 out of 3,539 
1 out of 289 
Years Active: 2018-2025
Title: Marie Pancera: Innovator in Viral Research
Introduction
Marie Pancera is a prominent inventor based in Seattle, WA (US), known for her significant contributions to the field of viral research. With a total of 10 patents, she has made remarkable strides in developing innovative solutions for combating viral infections, particularly Respiratory Syncytial Virus (RSV) and HIV-1.
Latest Patents
Among her latest patents is the development of prefusion RSV F proteins and their use. This invention provides embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation. The patent also discloses nucleic acids encoding the RSV F ectodomain trimer and methods for producing it. Furthermore, methods for inducing an immune response in a subject are outlined, which can be utilized for treating or preventing RSV infections by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer. Another significant patent involves recombinant HIV-1 envelope proteins and their use. This patent describes HIV-1 Env ectodomain trimers stabilized in a prefusion mature closed conformation, along with methods for their use and production. These innovations can generate an immune response to HIV-1 in a subject and can be administered to treat or prevent HIV-1 infection.
Career Highlights
Marie has worked with esteemed organizations such as the National Institutes of Health, a component of the US Department of Health & Human Services, and the Fred Hutchinson Cancer Center. Her work in these institutions has been pivotal in advancing research in viral immunology and vaccine development.
Collaborations
Throughout her career, Marie has collaborated with notable colleagues, including Ivelin Georgiev and Michael Gordon Joyce. These partnerships have contributed to her success and the impact of her research in the scientific community.
Conclusion
Marie Pancera's innovative work in viral research has led to significant advancements in the development of vaccines and treatments for RSV and HIV-1. Her contributions continue to shape the future of virology and immunology.