The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2024
Filed:
Sep. 11, 2023
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Peter D. Kwong, Washington, DC (US);
Barney S. Graham, Smyrna, GA (US);
Jason S. McLellan, Austin, TX (US);
Jeffrey Boyington, Clarksburg, MD (US);
Lei Chen, Rockville, MD (US);
Man Chen, Clarksburg, MD (US);
Gwo-Yu Chuang, Rockville, MD (US);
Ivelin Stefanov Georgiev, Nashville, TN (US);
Jason Gorman, Silver Spring, MD (US);
Michael Gordon Joyce, Washington, DC (US);
Masaru Kanekiyo, North Bethesda, MD (US);
Gilad Ofek, Gaithersburg, MD (US);
Marie Pancera, Seattle, WA (US);
Mallika Sastry, Rockville, MD (US);
Cinque Soto, Rockville, MD (US);
Sanjay Srivatsan, Lilburn, GA (US);
Guillaume Stewart-Jones, Cambridge, MA (US);
Yongping Yang, Potomac, MD (US);
Baoshan Zhang, Bethesda, MD (US);
Tongqing Zhou, Boyds, MD (US);
Abstract
Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.