Maria J P Van Dongen

Title: **Maria J P Van Dongen: Innovator in S1P Modulators**

Introduction

Maria J P Van Dongen is a notable inventor based in Hoofddorp, Netherlands, with an impressive portfolio of 8 patents. His contributions predominantly focus on spiro-cyclic amine derivatives and fused heterocyclic compounds, highlighting their application in pharmaceutical advancements.

Latest Patents

One of his latest patents, titled "Spiro-cyclic amine derivatives as S1P modulators," involves novel spiro-cyclic amine derivatives characterized by specific formula parameters. These compounds exhibit high affinity for S1P receptors, which may be utilized in the treatment, alleviation, or prevention of various diseases connected to S1P receptor activity.

Another significant patent, "Fused heterocyclic derivatives as S1P modulators," presents new fused heterocyclic derivatives that also target S1P receptors. This invention includes pharmaceutical compositions containing these compounds and outlines their therapeutic potential for diseases linked to S1P receptor modulation.

Career Highlights

Maria has had a substantial impact in the pharmaceutical field, notably through his work with AbbVie B.V. and AbbVie Inc., where his innovative research has contributed to the development of valuable medicinal compounds.

Collaborations

Throughout his career, Maria has collaborated with esteemed colleagues, including Wouter I Iwema Bakker and Hein K A C Coolen. These partnerships have fostered a rich exchange of ideas and advancements in their field of research.

Conclusion

Overall, Maria J P Van Dongen stands out as a dedicated inventor with a keen focus on creating compounds that hold significant promise for medical treatments. His ongoing work continues to influence the realm of pharmacology, enhancing the understanding and application of S1P modulation in addressing critical health challenges.