Inventors with similar research interests:
Location History:
- Dearfield, WI (US) (2011)
- Madison, WI (US) (2003 - 2012)
- Deerfield, WI (US) (2000 - 2023)
Company Filing History:
104 out of 4,119 
2 out of 827 
1 out of 15,458 
Years Active: 2000-2023
Title: Margaret Clagett-Dame: Pioneering Innovator in Crystallization Techniques and Vitamin D Analogs
Introduction:
Margaret Clagett-Dame, hailing from Deerfield, WI (US), is a highly accomplished inventor and researcher in the field of crystallization techniques and vitamin D analogs. With an impressive portfolio of 105 patents, Clagett-Dame has made significant contributions to the scientific community through her groundbreaking discoveries. This article will shed light on her latest patents, career highlights, collaborative efforts, and her remarkable achievements.
Latest Patents:
Clagett-Dame's recent patents showcase her expertise in the purification and synthesis of complex molecules with medicinal potential. One of her noteworthy inventions is the "Procedure for crystallization of (22E)-(24R)-2-methylene-22-dehydro-1α,24,25-trihydroxy-19-nor-vitamin D." This patent details methods for obtaining this compound in crystalline form, which is crucial for pharmaceutical applications. By dissolving the compound in a specific solvent combination, allowing crystals to form and precipitate, and subsequently recovering the crystals, Clagett-Dame has provided an important breakthrough in the purification process.
Another significant invention by Clagett-Dame is the "2-methylene-(22E)-25-hexanoyl-24-oxo-26,27-cyclo-22-dehydro-19-nor-vitamin D analogs." This patent describes analog compounds with promising pharmaceutical uses, particularly in treating skin diseases like psoriasis and addressing conditions such as wrinkles, slack skin, dry skin, and insufficient sebum secretion. These compounds also exhibit low activity in mobilizing bone calcium, making them potential candidates for treating autoimmune disorders, inflammatory diseases, and even obesity.
Career Highlights:
Throughout her career, Clagett-Dame has made substantial contributions to various research institutions and organizations. Notably, she has collaborated with the esteemed Wisconsin Alumni Research Foundation (WARF) and The Ohio State University Research Foundation. Her association with these prestigious institutions reflects her dedication to advancing scientific knowledge and applying it in practical ways.
Collaborations:
Clagett-Dame has had the privilege of working with accomplished peers, including notable individuals such as Hector Floyd Deluca and Lori A. Plum. Collaborating with experts in the field has allowed her to leverage their collective expertise, contributing to the development of innovative solutions and pioneering research in her domain.
Conclusion:
Margaret Clagett-Dame's exceptional career is a testament to her unwavering commitment to innovation and research. With over 100 patents to her name, her contributions in the fields of crystallization techniques and vitamin D analogs have significantly advanced scientific knowledge. Her latest patents focusing on the purification of complex compounds and the synthesis of analogs capable of addressing various health conditions reveal her instrumental role in pushing the boundaries of knowledge and medical advancements. Clagett-Dame's collaborations with esteemed organizations and visionary colleagues further emphasize her dedication to the scientific community. Her remarkable achievements continue to inspire future generations of inventors and researchers in their pursuit of groundbreaking innovations and patents.
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