Margaret C Bash

Title: The Innovative Contributions of Margaret C. Bash

Introduction

Margaret C. Bash is a prominent inventor based in Silver Spring, MD (US). She has made significant contributions to the field of immunology, particularly through her innovative patents. With a total of two patents to her name, her work focuses on developing immunogenic compositions that can induce immune responses.

Latest Patents

Margaret C. Bash's latest patents include groundbreaking immunogenic compositions. One patent discloses immunogenic compositions that include microvesicles, such as outer membrane vesicles (OMV) and/or blebs, derived from PorAPorB, such as PorAPorBRmpM. These compositions are designed to elicit an immune response. Another patent describes immunogenic compositions that feature a bacterial capsular polysaccharide conjugated to a carrier protein. In some embodiments, the bacterial capsular polysaccharide is an acapsular polysaccharide. The carrier protein includes a factor H binding protein (fHbp) linked to cholera toxin subunit B (CTB). The administration of these immunogenic compositions is intended to produce meningococcal polysaccharide-specific and fHbp-specific antibodies, with potential applications as meningococcal vaccines.

Career Highlights

Margaret C. Bash is affiliated with the National Institutes of Health, a component of the US Department of Health & Human Services. Her work at this esteemed institution has allowed her to focus on research that has the potential to impact public health significantly.

Collaborations

Margaret has collaborated with notable colleagues, including Kathryn Matthias and Gregory Price. These collaborations have likely contributed to the advancement of her research and the development of her patents.

Conclusion

Margaret C. Bash's innovative work in immunogenic compositions showcases her dedication to advancing medical science. Her contributions have the potential to lead to significant improvements in vaccine development and public health.