Location History:
- Segrate (MI), IT (2014)
- Segrate, IT (2014)
Company Filing History:
Years Active: 2014
Title: **Marco Silvagni: Innovator in Protein Kinase Inhibition**
Introduction
Marco Silvagni, an accomplished inventor based in Segrate (MI), Italy, has significantly contributed to the field of pharmaceutical sciences. With a focus on innovative compounds aimed at inhibiting protein kinase activity, he holds two notable patents that showcase his expertise and dedication to advancing therapeutic options for various diseases.
Latest Patents
Silvagni's recent patents include cutting-edge inventions that offer new solutions for treating conditions linked to dysregulated protein kinase activity. The first patent, titled "Tricyclic derivatives, process for their preparation and their use as kinase inhibitors," describes novel substituted tricyclic compounds characterized by specific groups (R1, R2, X, Y, Z) that exhibit protein kinase inhibiting activity. This invention encompasses methods for synthesizing these compounds, creating pharmaceutical compositions, and employing them in therapeutic contexts, particularly targeting diseases associated with protein kinase dysregulation.
His second patent, focusing on "Pyrazolo-quinazolines," details unique compounds marked by an ortho-substituted-arylamino, heterocyclylamino, or cycloalkylamino residue at the 8th position, alongside an aryl or heterocyclic group as a carboxamide substituent at the 3rd position of the molecular framework. These compounds are designed to modulate protein kinase activity, making them valuable for treating disorders related to MPS1/TTK. Similar to his first patent, this invention also outlines methods for preparation, pharmaceutical formulations, and therapeutic applications.
Career Highlights
Marco Silvagni is presently associated with Nerviano Medical Sciences S.r.l., where he channels his expertise into research and development. His work has positioned him as a key player in the advancement of pharmaceutical innovations that intersect with kinase inhibition and disease management.
Collaborations
In the course of his career, Silvagni has collaborated with esteemed colleagues, including Marina Caldarelli and Francesco Casuscelli. Together, they contribute to the dynamic research environment at Nerviano Medical Sciences, fostering innovation and pushing the boundaries of modern medicine.
Conclusion
Marco Silvagni stands as a noteworthy inventor in the realm of pharmaceutical research, particularly in the development of kinase inhibitors. Through his innovative patents and collaborative efforts, he plays a crucial role in addressing significant medical challenges, demonstrating the power of invention in enhancing human health. His dedication and contributions are pivotal to the ongoing evolution of therapeutic strategies aimed at treating complex diseases.