Location History:
- Philadelphia, PA (US) (2017 - 2019)
- Ardmore, PA (US) (2020 - 2024)
Company Filing History:
Years Active: 2017-2025
Title: Marco Ruella: Innovator in Chimeric Antigen Receptor Therapies
Introduction
Marco Ruella is a prominent inventor based in Ardmore, PA (US), known for his significant contributions to the field of immunotherapy. He holds a total of 15 patents, focusing on innovative therapies that target specific antigens in the treatment of various diseases.
Latest Patents
Among his latest patents are groundbreaking therapies involving CD20, CD22, and combination therapies utilizing a CD19 chimeric antigen receptor (CAR)-expressing cell. These inventions provide compositions and methods for treating diseases associated with the expression of CD19. The approach includes administering a recombinant T cell comprising the CD19 CAR, in combination with one or more B-cell inhibitors. Additionally, his patents feature novel antigen binding domains and CAR molecules directed to CD20 and CD22, which can be used as monotherapies or in combination therapies. Another notable invention includes the use of CD2/5/7 knock-out anti-CD2/5/7 chimeric antigen receptor T cells against T cell lymphomas and leukemias, showcasing his commitment to advancing cancer treatment.
Career Highlights
Marco Ruella has worked with esteemed organizations such as the University of Pennsylvania and Novartis AG. His work in these institutions has allowed him to develop and refine his innovative therapies, contributing to the advancement of medical science.
Collaborations
Throughout his career, Marco has collaborated with notable colleagues, including Jennifer Brogdon and Saar Gill. These partnerships have played a crucial role in the development of his patented technologies.
Conclusion
Marco Ruella's contributions to the field of immunotherapy through his innovative patents and collaborations highlight his dedication to improving treatment options for patients. His work continues to influence the landscape of medical research and therapy development.