The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
Jun. 25, 2021
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Novartis Ag, Basel, CH;
Jennifer Brogdon, Sudbury, MA (US);
Eugene Choi, Cambridge, MA (US);
Hilmar Erhard Ebersbach, Basel, CH;
David Jonathan Glass, Cambridge, MA (US);
Heather Huet, Arlington, MA (US);
Carl H. June, Merion Station, PA (US);
Joan Mannick, Cambridge, MA (US);
Michael C. Milone, Moorestown, NJ (US);
Leon Murphy, Cambridge, MA (US);
Gabriela Plesa, Blue Bell, PA (US);
Celeste Richardson, Cambridge, MA (US);
Marco Ruella, Ardmore, PA (US);
Reshma Singh, Cambridge, MA (US);
Yongqiang Wang, Shanghai, CN;
Qilong Wu, Shanghai, CN;
Novartis AG, Basel, CH;
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Abstract
The invention provides compositions and methods for treating diseases associated with expression of BCMA. The invention also relates to chimeric antigen receptor (CAR) specific to BCMA vectors encoding the same, and recombinant T cells comprising the BCMA CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a BCMA binding domain.