New York, NY, United States of America

Marcel Van Den Brink

USPTO Granted Patents = 8 

 

 

Average Co-Inventor Count = 3.7

ph-index = 1

Forward Citations = 1(Granted Patents)


Company Filing History:


Years Active: 2015-2025

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8 patents (USPTO):Explore Patents

Title: Marcel Van Den Brink: Innovator in Hematopoietic Stem Cell Research

Introduction

Marcel Van Den Brink is a prominent inventor based in New York, NY (US). He has made significant contributions to the field of hematopoietic stem cell research, holding a total of 8 patents. His work focuses on innovative methods and compositions that enhance the understanding and treatment of various malignancies.

Latest Patents

One of his latest patents involves the use of luteinizing hormone receptor (LHR) binding agents and luteinizing hormone (LH) agonists. This invention aims to identify, expand, ablate, and modify stem cells, particularly primitive hematopoietic stem cell (pHSC) populations. The methods described can prepare therapeutic hematopoietic stem cell (HSC) populations, facilitate patient preparation for therapeutic HSC transplants, and treat malignancies associated with hyperproliferative HSC.

Another significant patent focuses on methods and compositions for identifying and treating subjects at risk for poor CAR T cell therapy response. This invention relates to analyzing the intestinal microbiome of subjects to predict their response to CAR T cell therapy. It provides a method for detecting patients at risk for a poor response by measuring specific bacteria or bacterial genes in their microflora. Additionally, it offers therapeutic compositions and methods to improve the response of cancer patients to CAR T cell therapy.

Career Highlights

Marcel has worked with esteemed institutions such as Memorial Sloan Kettering Cancer Center and Fred Hutchinson Cancer Center. His career is marked by a commitment to advancing the field of cancer treatment through innovative research and development.

Collaborations

Throughout his career, Marcel has collaborated with notable colleagues, including Jarrod Dudakov and Alan Hanash. These partnerships have contributed to the success of his research and the development of his patents.

Conclusion

Marcel Van Den Brink is a distinguished inventor whose work in hematopoietic stem cell research has the potential to transform cancer treatment. His innovative patents and collaborations highlight his dedication to improving patient outcomes in the field of oncology.

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