Company Filing History:
Years Active: 2018-2019
Title: The Innovative Contributions of Manoj Kumar Chhikara
Introduction
Manoj Kumar Chhikara is a prominent inventor based in Delhi, India. He has made significant contributions to the field of chemical synthesis, particularly in the development of novel oligomers for medical applications. With a total of 3 patents to his name, his work focuses on creating solutions for bacterial infections, specifically targeting meningitis.
Latest Patents
Chhikara's latest patents include groundbreaking inventions related to the synthesis of higher oligomers. One of his notable inventions pertains to the chemical synthesis of oligomers of serogroup X, which are crucial for developing conjugate vaccines against bacterial meningitis caused by Men-X infections. This invention provides a synthetic pathway using purified saccharides of specific chain lengths to create Men-X capsular oligomers.
Another significant patent involves an improved process of conjugation to obtain synthetic oligosaccharide-protein conjugates. This rapid process yields highly immunogenic oligosaccharide-protein conjugates that elicit specific and homogenous immune responses. The synthetic oligosaccharides mimic natural polysaccharides obtained from gram-negative bacteria, and the conjugation chemistry utilizes thio-ether linkages. The entire process takes approximately 14-22 hours, making it efficient for vaccine production and diagnostic tools.
Career Highlights
Chhikara is currently associated with Msd Wellcome Trust Hilleman Laboratories Pvt. Ltd., where he continues to innovate in the field of vaccine development. His work is instrumental in advancing medical research and improving public health outcomes.
Collaborations
Throughout his career, Chhikara has collaborated with notable colleagues, including Davinder Gill and Rakesh Rana. These partnerships have fostered a collaborative environment that enhances the research and development of innovative solutions in the medical field.
Conclusion
Manoj Kumar Chhikara's contributions to the field of chemical synthesis and vaccine development are noteworthy. His innovative patents and collaborative efforts continue to make a significant impact on public health.