IDiyas

For the Inventor, By the Inventor

Belmont, MA, United States of America

Manami Shizuka

LinkedIn
USPTO Granted Patents = 30 

 

 

Average Co-Inventor Count = 4.4

ph-index = 3

Forward Citations = 45(Granted Patents)


Location History:

  • Lexington, MA (US) (2014 - 2017)
  • Belmont, MA (US) (2016 - 2024)

Company Filing History:

goldMedal24 out of 255 
 
Immunogen, Inc.
 patents
silverMedal6 out of 2,405 
 
Merck Sharp + Dohme Corp.
 patents

Years Active: 2014-2024

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30 patents (USPTO):
1. 11981687 - Methods of preparing cytotoxic benzodiazepine derivatives (2024-05-14),
2. 11793885 - Substituted benzo[5,6][1,4]diazepino[1,2-a]indoles for the treatment of proliferative disorders (2023-10-24),
3. 11760759 - Process for preparing substituted indolines (2023-09-19),
4. 11732038 - Conjugates comprising cell-binding agents and cytotoxic agents (2023-08-22),
5. 11420982 - Methods of preparing cytotoxic benzodiazepine derivatives (2022-08-23),
6. 11390633 - Methods of preparing cytotoxic benzodiazepine derivatives (2022-07-19),
7. 11116845 - Cytotoxic benzodiazepine derivatives (2021-09-14),
8. 10988531 - Conjugates comprising cell-binding agents and cytotoxic agents (2021-04-27),
9. 10968228 - Methods of preparing substituted 12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indoles (2021-04-06),
10. 10899775 - Methods of preparing cytotoxic benzodiazepine derivatives (2021-01-26),
11. 10844078 - Methods of preparing cytotoxic benzodiazepine derivatives (2020-11-24),
12. 10787463 - Methods of preparing cytotoxic benzodiazepine derivatives (2020-09-29),
13. 10722588 - Cytotoxic benzodiazepine derivatives (2020-07-28),
14. 10442809 - Methods for preparing substituted 12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-ones (2019-10-15),
15. 10392407 - Methods of preparing cytotoxic benzodiazepine derivatives (2019-08-27),

Title: Manami Shizuka: Innovator in Benzodiazepine Derivatives

Introduction

Manami Shizuka, based in Belmont, MA, is an important figure in the field of pharmaceutical innovations. With an impressive portfolio of 24 patents, Shizuka has made significant contributions to the development of novel therapeutic compounds aimed at treating various medical conditions.

Latest Patents

Among his latest patents, two notable inventions stand out. The first is titled "Methods of Preparing Cytotoxic Benzodiazepine Derivatives," which provides innovative methods for synthesizing indolinobenzodiazepine dimer compounds and their precursors. The second patent, "Substituted Benzo[5,6][1,4]diazepino[1,2-a]indoles for the Treatment of Proliferative Disorders," focuses on new benzodiazepine derivatives that display antiproliferative activity. This invention includes compositions and methods that aim to inhibit abnormal cell growth and treat proliferative disorders in mammals.

Career Highlights

Shizuka is currently engaged with Immunogen, Inc., a company known for its advancements in drug development utilizing antibody-drug conjugate technologies. His work at Immunogen represents a blend of innovative research and practical applications aimed at enhancing cancer treatment options.

Collaborations

Throughout his career, Manami Shizuka has collaborated with several esteemed colleagues, including Michael Louis Miller and Baudouin Gérard. These partnerships contribute to a dynamic exchange of ideas and foster advancements in their joint research endeavors.

Conclusion

Manami Shizuka's commitment to innovation and research continues to pave the way for advancements in medicinal chemistry. His significant contributions in developing new therapeutic compounds showcase the vital role that inventors like him play in improving healthcare outcomes.

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