Company Filing History:
Years Active: 1994-1998
Title: Innovations of Man-Keun Kim in Antiviral Protein Research
Introduction
Man-Keun Kim is a prominent inventor based in Seoul, South Korea. He has made significant contributions to the field of biotechnology, particularly in the development of antiviral proteins. With a total of five patents to his name, Kim's work focuses on innovative solutions for enhancing plant resistance to viruses.
Latest Patents
Among his latest patents is the discovery of a novel genome coding for the Phytolacca insularis antiviral protein (PIP). This protein was isolated from the plant Phytolacca insularis Nakai. Kim and his team developed a recombinant vector for the expression of the PIP genome, which has shown a nucleotide homology of about 82% with the genome of the Phytolacca americana antiviral protein. The PIP cDNA consists of 918 base pairs, including one open reading frame and a termination codon. Additionally, a polyadenylation signal, which is common in the mRNA of most plants and animals, is located upstream of 33 base pairs from the polyadenylation site. The recombinant PIP has been proven to inhibit the growth of E. coli HB101 transformed with the expression vector.
Another significant patent involves a process for preparing virus-resistant transgenic plants. This process utilizes a recombinant vector for the expression of the Phytolacca insularis antiviral protein. The invention grants broad viral resistance to transgenic plants transformed with the PIP expression vector, showcasing the potential for agricultural applications.
Career Highlights
Man-Keun Kim is associated with Jin Ro Limited, where he continues to advance his research in biotechnology. His innovative work has positioned him as a key figure in the field of antiviral protein research.
Collaborations
Kim has collaborated with notable colleagues, including Kyu-Whan Choi and Young-Ho Moon, who have contributed to his research endeavors.
Conclusion
Man-Keun Kim's contributions to the field of antiviral proteins highlight his innovative spirit and dedication to advancing biotechnology. His patents reflect a commitment to developing solutions that enhance plant resistance to viruses, paving the way for future agricultural advancements.