The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 1994

Filed:

Oct. 15, 1993
Applicant:
Inventors:

Young-Ho Moon, Kyunggi-Do, KR;

Hong-Seob Jeon, Seoul, KR;

Kyu-Whan Choi, Seoul, KR;

Kwan-Ho Lee, Seoul, KR;

Man-Keun Kim, Seoul, KR;

Assignee:

Jinro Limited, Seocho-ku, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 691 ; 435 713 ; 435199 ; 4352523 ; 43525233 ; 4353201 ; 4351723 ; 536 232 ; 536 236 ; 935 11 ; 935 14 ; 935 29 ; 935 56 ; 935 72 ; 935 73 ;
Abstract

The present inventors discovered a novel genome coding Phytolacca insularis antiviral protein(PIP) isolated from Phytolacca insularis Nakai; and developed a recombinant vector for said PIP genome expression and a microorganism transformed therewith. PIP genome of the present invention has nucleotide hornology of about 82%, compared with the genome of Phytolacca americana antiviral protein isolated from Phytolacca americana L., which is closely related to the Phytolacca insularis Nakai. PIP cDNA is consist of 918 bp of one open reading frame and termination codon; and polyaclenylation signal which is ubiquitous in mRNA of most plants and animals, appears to be located in the upstream of 33 bp from the polyadenylation site. Recombinant PIP of the invention was proved to inhibit the growth of E. coli HB101 transformed with said expression vector.


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