Company Filing History:
Years Active: 1999-2007
Title: **Innovative Contributions of Inventor Malayannan Subramaniam**
Introduction
Malayannan Subramaniam, based in Zumbrota, Minnesota, is an accomplished inventor known for his significant contributions to biomedical research. With three patents to his name, Subramaniam has been at the forefront of innovations that address critical health issues, particularly relating to cardiac conditions and cancer detection.
Latest Patents
One of Subramaniam's latest patents involves the creation of transgenic TIEG non-human animals. This invention encompasses materials and methods related to non-human mammals that possess a disrupted TIEG allele in their genome. The significance of this work lies in its application for identifying and characterizing agents that influence conditions associated with TIEG activity, such as cardiac hypertrophy and bone formation. Furthermore, this patent also includes methods for the treatment of hypertrophic cardiomyopathy.
Another notable patent covers TGF-β inducible early factor-1 (TIEF-1) and presents innovative methods for detecting breast cancer. This involves determining TIEF-1 polypeptides or identifying genetic rearrangements in the TIEF-1 gene within a sample. The patent also introduces TIEF-1 specific antibodies and nucleic acid probes, which can be employed to detect breast cancer in situ within mammalian tissue samples, enhancing early diagnosis and treatment.
Career Highlights
Malayannan Subramaniam is currently affiliated with the Mayo Foundation for Medical Education and Research, where he continues to develop groundbreaking methodologies that hold the potential to transform the field of medical research. His work not only enhances our understanding of certain medical conditions but also paves the way for innovative treatments.
Collaborations
Throughout his career, Subramaniam has collaborated with esteemed colleagues such as Thomas C. Spelsberg and Patrick C. Roche. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.
Conclusion
Malayannan Subramaniam exemplifies the spirit of innovation in the medical field. His patents reflect a commitment to addressing some of the most pressing health challenges today. Through his work at the Mayo Foundation for Medical Education and Research, Subramaniam not only pushes the boundaries of scientific research but also provides hope for improved medical outcomes for patients worldwide.