The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2007
Filed:
Sep. 17, 2004
Thomas C. Spelsberg, Rochester, MN (US);
Malayannan Subramaniam, Zumbrota, MN (US);
Merry JO Velasquez, Cannon Falls, MN (US);
Nalini M. Rajamannan, Chicago, IL (US);
Thomas C. Spelsberg, Rochester, MN (US);
Malayannan Subramaniam, Zumbrota, MN (US);
Merry Jo Velasquez, Cannon Falls, MN (US);
Nalini M. Rajamannan, Chicago, IL (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Abstract
Materials and methods related to a transgenic non-human animal (e.g., a transgenic non-human mammal) whose genome comprises a disrupted TIEG allele are provided. Methods for making such transgenic non-human animals, and using them to identify and characterize agents that affect conditions related to TIEG activity, such as cardiac hypertrophy and bone formation also are provided. In addition, materials and methods related to the treatment of hypertrophic cardiomyopathy are provided.