Company Filing History:
5 out of 651 
3 out of 827 
3 out of 3 
Years Active: 1984-2025
Title: Innovations of Ly James Lee
Introduction
Ly James Lee is a prominent inventor based in Columbus, Ohio. He has made significant contributions to the field of biotechnology, particularly in the development of methods for producing therapeutic exosomes and detecting mutated genes. With a total of 14 patents to his name, his work has the potential to impact medical diagnostics and treatment.
Latest Patents
One of his latest patents is a method for producing therapeutic exosomes from nanoelectroporation and other non-endocytic cell transfection. This innovative approach allows for the production of therapeutic extracellular vesicles (EVs) containing high copies of functional nucleic acids and other biomolecules. The process involves laying donor cells on a chip surface, adding various plasmids and transfection vectors, applying a pulsulatic electric field, and collecting the EVs secreted by the transfected cells. The chip features a three-dimensional (3D) nanochannel electroporation (NEP) biochip, which is designed to handle large quantities of donor cells.
Another significant patent involves highly stable and specific molecular beacons encapsulated in cationic lipoplex nanoparticles. This invention provides a method for detecting the presence of mutated genes, mRNAs, or microRNAs in a subject. The method includes providing a body fluid sample and using an analyzer with overhang molecular beacons to measure fluorescence signals, thereby detecting the presence of the mutated genetic material.
Career Highlights
Ly James Lee has worked with notable organizations such as the Ohio State Innovation Foundation and The Ohio State University. His career reflects a commitment to advancing biotechnological research and innovation.
Collaborations
He has collaborated with esteemed colleagues, including Nan-Rong Chiou and Kwang Joo Kwak, contributing to the advancement of his research and inventions.
Conclusion
Ly James Lee's innovative work in biotechnology, particularly in the production of therapeutic exosomes and the detection of genetic mutations, showcases his significant contributions to the field. His patents reflect a dedication to improving medical diagnostics and treatment options.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.