The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2023
Filed:
Dec. 20, 2017
Applicant:
Ohio State Innovation Foundation, Columbus, OH (US);
Inventors:
Daniel Gallego-Perez, Columbus, OH (US);
Ly James Lee, Columbus, OH (US);
Durba Pal, Kolkata, IN;
Subhadip Ghatak, Columbus, OH (US);
Chandan Sen, Upper Arlington, OH (US);
Assignee:
Ohio State Innovation Foundation, Columbus, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/79 (2006.01); C07H 21/04 (2006.01); C07K 14/47 (2006.01); C12N 5/071 (2010.01); C12N 15/85 (2006.01); A61K 48/00 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); C12N 5/069 (2013.01); C12N 15/85 (2013.01); A61K 48/00 (2013.01); C07H 21/02 (2013.01); C07H 21/04 (2013.01); C12N 2506/1307 (2013.01);
Abstract
Disclosed herein are compositions and methods that involve using compositions containing one or more of ETV2, FOXC2, FLI1 and a miR-200b inhibitor for directly reprogramming somatic cells into induced vasculogenic cells both in vitro and in vivo. These compositions and methods are useful for a variety of purposes, including the development of pro-angiogenic therapies.