Company Filing History:
Years Active: 1993-1995
Title: Luis A Melendez: Innovator in Biological Sample Disruption and Cell Mechanics
Introduction
Luis A Melendez is a notable inventor based in Norwood, MA (US). He has made significant contributions to the field of biological sample processing and cell mechanics, holding a total of 3 patents. His innovative approaches have the potential to enhance research and applications in cellular biology.
Latest Patents
One of his latest patents is the "Cell Disrupting Apparatus." This improved apparatus effectively disrupts biological samples contained in cuvettes with added beads. The design features a special arm/bearing subassembly that is driven and oscillated by a motor, achieving cellular disruption without degrading the cellular components. The apparatus includes a cam, bearings, and a bearing sleeve that work together with a motor drive shaft to rotate a yoke holding four cuvettes. For enhanced safety and environmental protection, the apparatus is designed with special sample retainers and is enclosed in a sample chamber that provides secondary containment for any spillage.
Another significant patent is the "Cell Stretching Method." This method imparts biaxial mechanical forces to living cell cultures, mimicking the mechanical forces experienced in vivo. The method utilizes a displacement applicator that contacts and stretches a membrane with a living cell culture mounted on it. This stretching can uniformly or selectively apply mechanical forces to the cells, which is crucial for various biological studies.
Career Highlights
Luis A Melendez has worked with prestigious organizations, including The General Hospital Corporation and the Massachusetts Institute of Technology. His experience in these institutions has allowed him to develop and refine his innovative ideas in biological research.
Collaborations
Throughout his career, Melendez has collaborated with esteemed colleagues such as Alan R Shapiro and Martha L Gray. These collaborations have contributed to the advancement of his research and inventions.
Conclusion
Luis A Melendez is a prominent inventor whose work in biological sample disruption and cell mechanics has made a significant impact in the field. His innovative patents and collaborations reflect his dedication to advancing scientific research and technology.