The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 1995

Filed:

Mar. 14, 1994
Applicant:
Inventors:

Luis A Melendez, Norwood, MA (US);

Robert E Rosenbaum, Framingham, MA (US);

Marcela A Vera-Garcia, Framingham, MA (US);

D Michael Olive, Framingham, MA (US);

John E Swenson, Marlboro, MA (US);

Assignee:

Amoco Corporation, Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M / ;
U.S. Cl.
CPC ...
4353061 ; 435259 ; 4352831 ; 241-2 ; 241175 ; 366209 ;
Abstract

An improved apparatus for effectively disrupting biological samples contained in cuvettes to which beads have been added. In the apparatus, a special arm/bearing subassembly is driven and oscillated by a motor in a manner to attain cellular disruption of the biological samples without degradation of their cellular components. In the preferred form, the special arm/bearing subassembly has a cam, bearings, and a bearing sleeve which cooperate with a motor drive shaft to rotate a yoke with two arms holding four cuvettes. For increased safety and environmental protection, special sample retainers can be provided to better secure the cuvettes and the arm/bearing subassembly is enclosed in a sample chamber which provides a secondary containment compartment that contain any spillage.


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