The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 1994
Filed:
Feb. 19, 1993
Alan R Shapiro, Sharon, MA (US);
Martha L Gray, Cambridge, MA (US);
Luis A Melendez, Norwood, MA (US);
Jonathan L Schaffer, Newton, MA (US);
Wright John D, Sandown, NH (US);
Jose G Venegas, Swampscott, MA (US);
The General Hospital Corporation, Cambridge, MA (US);
Massachusetts Institute of Technology, Boston, MA (US);
Abstract
Disclosed is a method for imparting to a living culture of cells biaxial mechanical forces which approximate the mechanical forces to which cells are subject in vivo. The method utilizes a displacement applicator which may be actuated to contact and stretch a membrane having a living cell culture mounted thereon. Stretching of the membrane imparts biaxial mechanical forces to the cells. These forces may be uniformly applied to the cells, or they may be selectively nonuniformly applied.