Luciano Mueller

Title: Luciano Mueller: Innovator in Biologics and Protein-Ligand Interactions

Introduction

Luciano Mueller is a prominent inventor based in Princeton, NJ (US), known for his significant contributions to the fields of biologics and protein-ligand interactions. With a total of 4 patents, he has developed innovative methods and compositions that enhance our understanding of molecular interactions and disease pathology.

Latest Patents

Among his latest patents, Mueller has developed "Methods and compositions for deuterated biologics," which includes deuterated polymer-biomolecule conjugates. This invention focuses on the synthesis and use of these conjugates for detecting the location of specific molecules, such as cell surface molecules, within a subject. It also aids in imaging various processes within the body, detecting molecules associated with disease pathology, and monitoring disease progression. Another notable patent is "Protein-ligand NOE matching for high-throughput structure determination." This method enhances the throughput and applicability of NMR-based structure determination of protein-ligand complexes. It circumvents the need for protein sequence-specific resonance assignments and integrates NMR data analysis with ligand docking methods, providing structural information in a high-throughput manner.

Career Highlights

Throughout his career, Luciano Mueller has worked with notable companies, including Bristol-Myers Squibb Company. His work has significantly impacted the field of molecular biology and drug development.

Collaborations

Mueller has collaborated with esteemed colleagues, including Keith Lewis Constantine and Brian Lee Claus, contributing to advancements in his research areas.

Conclusion

Luciano Mueller's innovative work in biologics and protein-ligand interactions showcases his dedication to advancing scientific knowledge and improving disease detection and monitoring. His contributions continue to influence the fields of molecular biology and pharmacology.