Luciano Forni

Title: Luciano Forni: Innovator in Peptide Synthesis

Introduction

Luciano Forni is a notable inventor based in La Louvière, Belgium. He has made significant contributions to the field of peptide synthesis, holding a total of 3 patents. His work focuses on innovative methods for preparing peptides, which are essential in various biomedical applications.

Latest Patents

One of Forni's latest patents is titled "Method for preparation of peptides with psWang linker." This invention discloses a method for the preparation of a peptide by liquid phase coupling of two fragments, an N-terminal fragment and a C-terminal fragment of the desired peptide. In this method, the C-terminal fragment is protected on its C-terminal COOH by a psWang linker. The method is demonstrated with liraglutide, wherein the C-terminal fragment carries the Palmitoyl-Glu-OtBu residue on the Lys. Another significant patent is "Process for the production of bivalirudin." This invention relates to a process for producing bivalirudin, a 20-mer peptide with the formula H-(D)-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH (SEQ ID NO: 1).

Career Highlights

Throughout his career, Luciano Forni has worked with prominent companies in the biotechnology sector. He has been associated with Polypeptide Laboratories Holding and Lonza Braine SA. His experience in these organizations has contributed to his expertise in peptide synthesis and innovation.

Collaborations

Forni has collaborated with notable professionals in his field, including Daniel Carbajo Lopez and Fernando Albericio Palomera. These collaborations have further enriched his research and development efforts in peptide technology.

Conclusion

Luciano Forni is a distinguished inventor whose work in peptide synthesis has led to valuable patents and advancements in the field. His contributions continue to influence the development of peptide-based therapies and applications.