The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
Jan. 20, 2017
Applicant:
Polypeptide Laboratories Holding (Ppl) Ab, Limhamn, SE;
Inventors:
Luciano Forni, La Louvière, BE;
Daniel Carbajo Lopez, Barcelona, ES;
Fernando Albericio Palomera, Barcelona, ES;
Assignee:
Polypeptide Laboratories Holding (PPL) AB, Limhamn, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 50/08 (2006.01); C07K 1/10 (2006.01); C07K 1/02 (2006.01); C07K 14/605 (2006.01);
U.S. Cl.
CPC ...
C07K 1/10 (2013.01); C07K 1/026 (2013.01); C07K 14/605 (2013.01);
Abstract
The invention discloses a method for the preparation of a peptide by liquid phase coupling of two fragments, an N-terminal fragment and a C-terminal fragment of the desired peptide, wherein the C-terminal fragment is protected on its C-terminal COOH by a psWang linker; the method is demonstrated with liraglutide wherein the C-terminal fragment carries the Palmitoyl-Glu-OtBu residue on the Lys.