Lois M Crowe

Title: The Innovative Contributions of Lois M Crowe

Introduction

Lois M Crowe is a distinguished inventor based in Davis, California, known for her significant contributions to the field of biochemistry and cell preservation. With a total of five patents to her name, she has made remarkable advancements in the preservation of erythrocytic cells, which are crucial for various medical applications.

Latest Patents

One of her latest patents focuses on erythrocytic cells and methods for preserving these cells. This patent describes a dehydrated composition that includes freeze-dried erythrocytic cells, where alcohol is at least partially removed from the cells, including their membranes. The resulting erythrocytic cells exhibit a low, intermediate, and high phase transition temperature range. Additionally, the cells can be loaded with oligosaccharides, such as trehalose, which help maintain their biological properties during freeze-drying and rehydration. Another innovative process she developed aims to prevent leakage and phase separation during thermotropic phase transitions by incorporating thermal hysteresis proteins, particularly antifreeze proteins from polar fish species.

Career Highlights

Lois M Crowe has had a notable career, working at prestigious institutions such as the University of California and the University of Southwestern Louisiana. Her research has significantly impacted the field of cell preservation, making her a respected figure among her peers.

Collaborations

Throughout her career, Lois has collaborated with esteemed colleagues, including John H Crowe and John F Carpenter. These collaborations have further enriched her research and contributed to her innovative work in cell preservation.

Conclusion

Lois M Crowe's contributions to the field of biochemistry and cell preservation are invaluable. Her innovative patents and collaborative efforts have paved the way for advancements in medical applications involving erythrocytic cells.