The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 1999
Filed:
Dec. 17, 1996
Lisa M Hays, Davis, CA (US);
John H Crowe, Davis, CA (US);
Lois M Crowe, Davis, CA (US);
Robert E Feeney, Davis, CA (US);
Ann E Oliver, Davis, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Leakage from liposomes or biological cells and structural damage, which occur upon cooling through the thermotropic phase transition temperature and upon storage at temperatures below the phase transition temperature are reduced or eliminated by incorporating thermal hysteresis proteins in the liposome or cell structure. Preferred thermal hysteresis proteins are antifreeze proteins and antifreeze glycoproteins from polar fish species, and chromatographic fraction no. 8 of antifreeze glycoproteins has been found to be particularly effective.