Location History:
- Goa, IN (2008)
- Dona Paula, IN (2011)
Company Filing History:
Years Active: 2008-2011
Title: Lisette D'Souza: Innovator in Antibacterial Compounds and Mannitol Production
Introduction
Lisette D'Souza is a prominent inventor based in Dona Paula, India. She has made significant contributions to the field of antibacterial compounds and the extraction of mannitol from mangrove-associated fungi. With a total of 2 patents, her work showcases her dedication to advancing scientific knowledge and practical applications in medicine.
Latest Patents
One of Lisette's latest patents involves a novel purified compound PM181104, which has a molecular weight of 1514 and a molecular formula of CHNOS. This compound is obtained through the fermentation of a microorganism belonging to the species ZMA B-1/MTCC 5269. The invention encompasses all stereoisomeric and tautomeric forms of PM181104, along with its pharmaceutically acceptable salts and derivatives, such as esters and ethers. Additionally, the patent details processes for producing this antibacterial compound and its use in pharmaceutical compositions aimed at treating and preventing diseases caused by bacterial infections.
Another significant patent relates to a plant mangrove-associated fungus and a method for obtaining high yields of pure mannitol. This method involves cutting leaves into small pieces and placing them on potato dextrose agar (PDA) plates for 48 hours. The culture is maintained at temperatures ranging from 26-47°C and salinity levels between 4-32 ppt, with occasional stress conditions for about 17-19 days to obtain a mycelial mat. The process includes sonicating the mat, extracting crude mannitol using methanol, and purifying it through chromatography to achieve a final product with about 75% purity.
Career Highlights
Lisette has worked with notable organizations, including the Council of Scientific & Industrial Research and Piramal Life Sciences Limited. Her experience in these institutions has contributed to her expertise in research and development in the field of microbiology and pharmaceuticals.
Collaborations
Throughout her career, Lisette has collaborated with esteemed colleagues, including Prabha Devi and Chandrakant Govind Naik. These partnerships have fostered innovation and enhanced the impact of her research.
Conclusion
Lisette D'Souza's contributions to the fields of antibacterial compounds and mannitol extraction highlight her role as an influential inventor. Her patents reflect her commitment