Lise Roth

Title: Lise Roth: Innovator in Peptide Research

Introduction

Lise Roth is a prominent inventor based in Strasbourg, France. She has made significant contributions to the field of peptide research, holding two patents that focus on innovative methods and compositions for targeting and internalizing molecules into cells.

Latest Patents

Lise Roth's latest patents include "Truncated LYP-1 peptides and methods and compositions using truncated LYP-1 peptides." This invention discloses compositions and methods that are useful for targeting and internalizing molecules into cells of interest, as well as for penetration by molecules into tissues of interest. The compositions are based on peptide sequences, such as truncated LyP-1 peptides, which are selectively internalized by cells and can penetrate tissues. This internalization and tissue penetration are beneficial for delivering therapeutic and detectable agents to specific cells and tissues. Another notable patent is "Peptidic antagonists of class III semaphorins/neuropilins complexes." This invention concerns a peptidic antagonist that comprises an amino acid sequence derived from the transmembrane domain of various proteins, including neuropilin-1 and neuropilin-2, among others. It includes at least a GxxxG motif and can be fused to a heterologous sequence, along with a nucleic acid encoding for the peptidic antagonist and its pharmaceutical applications.

Career Highlights

Throughout her career, Lise Roth has worked with esteemed institutions such as the Institut National de la Santé et de la Recherche Médicale and the Sanford-Burnham Medical Research Institute. Her work has significantly advanced the understanding of peptide interactions and their applications in medicine.

Collaborations

Lise has collaborated with notable colleagues, including Dominique Bagnard and Cécile Nasarre, contributing to a rich exchange of ideas and research in her field.

Conclusion

Lise Roth's innovative work in peptide research has led to valuable patents that enhance the delivery of therapeutic agents. Her contributions continue to impact the scientific community and pave the way for future advancements in medical research.