The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 15, 2019

Filed:

Aug. 24, 2012
Applicants:

Erkki Ruoslahti, Buellton, CA (US);

Tambet Teesalu, Goleta, CA (US);

Kazuki Sugahara, Goleta, CA (US);

Lise Roth, Strasbourg, FR;

Inventors:

Erkki Ruoslahti, Buellton, CA (US);

Tambet Teesalu, Goleta, CA (US);

Kazuki Sugahara, Goleta, CA (US);

Lise Roth, Strasbourg, FR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); A61K 31/337 (2006.01); C07K 7/08 (2006.01); C07K 14/47 (2006.01); A61K 38/08 (2006.01); A61K 45/06 (2006.01); A61K 47/62 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 31/337 (2013.01); A61K 38/08 (2013.01); A61K 45/06 (2013.01); A61K 47/62 (2017.08); A61K 47/6929 (2017.08); A61K 47/6953 (2017.08); C07K 7/08 (2013.01); C07K 14/4748 (2013.01);
Abstract

Disclosed are compositions and methods useful for targeting and internalizing molecules into cells of interest and for penetration by molecules of tissues of interest. The compositions and methods are based on peptide sequences, such as truncated LyP-1 peptides, that are selectively internalized by a cell, penetrate tissue, or both. The disclosed internalization and tissue penetration is useful for delivering therapeutic and detectable agents to cells and tissues of interest.


Find Patent Forward Citations

Loading…