The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2015

Filed:

Jun. 28, 2006
Applicants:

Dominique Bagnard, Colmar, FR;

Lise Roth, Strasbourg, FR;

Cécile Nasarre, Strasbourg, FR;

Pierre Hubert, Saint-Didier, FR;

Sylvie Dirrig-grosch, Lingolsheim, FR;

Gerard Cremel, Lingolsheim, FR;

Dominique Aunis, Strasbourg, FR;

Inventors:

Dominique Bagnard, Colmar, FR;

Lise Roth, Strasbourg, FR;

Cécile Nasarre, Strasbourg, FR;

Pierre Hubert, Saint-Didier, FR;

Sylvie Dirrig-Grosch, Lingolsheim, FR;

Gerard Cremel, Lingolsheim, FR;

Dominique Aunis, Strasbourg, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 7/00 (2006.01); C07K 14/71 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); C07K 7/00 (2013.01); A61K 38/00 (2013.01); C07K 14/70546 (2013.01);
Abstract

The present invention concern a peptidic antagonist of class III semaphorins/neuropilins complexes comprising an amino acid sequence, which is derived from the transmembrane domain of a protein selected in the group consisting of neuropilin-1, neuropilin-2, plexin-A1, plexin-A2, plexin-A3, plexin-A4, Nr-CAM, L1-CAM, integrin Beta 1 and integrin beta 2, and including at least a GxxxG motif, eventually fused to an heterologous sequence; a nucleic acid encoding for said peptidic antagonist, a pharmaceutical composition comprising such a peptidic antagonist or a nucleic acid encoding thereof and uses thereof.


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