San Diego, CA, United States of America

Linling He

USPTO Granted Patents = 15 

 

Average Co-Inventor Count = 3.4

ph-index = 2

Forward Citations = 29(Granted Patents)


Location History:

  • La Jolla, CA (US) (2021)
  • San Diego, CA (US) (2020 - 2024)

Company Filing History:


Years Active: 2020-2025

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15 patents (USPTO):Explore Patents

Title: Innovations and Contributions of Inventor Linling He

Introduction

Linling He is a prominent inventor based in San Diego, California. He has made significant contributions to the field of immunology, particularly in the development of vaccines targeting coronaviruses and other viral infections. With a total of 15 patents to his name, He has established himself as a key figure in the scientific community.

Latest Patents

One of Linling He's latest patents is focused on "Stabilized coronavirus spike (s) protein immunogens and related vaccines." This invention provides redesigned soluble coronavirus S protein-derived immunogens that are stabilized through specific modifications in the wildtype soluble S sequences. The patent also includes nanoparticle vaccines that contain these redesigned soluble S immunogens displayed on self-assembling nanoparticles. Additionally, it offers polynucleotide sequences encoding the redesigned immunogens and the nanoparticle vaccines, along with methods for using these vaccine compositions in various therapeutic applications, such as preventing or treating coronaviral infections.

Another notable patent is for "Nanoparticle vaccines with novel structural components." This invention presents novel nanoparticle vaccine compositions that are stabilized with a locking domain. Various immunogens can be utilized in the preparation of these vaccine compositions, including viral immunogens like HIV-1 and Ebola, as well as non-viral immunogens derived from bacteria, parasites, and mammalian species. The patent also outlines methods for using these vaccine compositions in therapeutic applications aimed at preventing or treating viral infections.

Career Highlights

Linling He has worked with esteemed organizations such as The Scripps Research Institute and the National Center for AIDS/STD Control and Prevention, which is part of the Chinese Center for Disease Control and Prevention. His work in these institutions has allowed him to contribute significantly to the advancement of vaccine technology and public health.

Collaborations

Some of Linling He's notable coworkers include Jiang Zhu and Ian A Wilson. Their collaborative efforts have further enhanced the research and development of innovative vaccine solutions.

Conclusion

Linling He is a distinguished inventor whose work in vaccine development has the potential to impact global health significantly. His innovative patents and collaborations reflect his commitment to advancing medical science and addressing pressing health challenges.

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