The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2023
Filed:
Dec. 16, 2021
The Scripps Research Institute, La Jolla, CA (US);
Leopold Kong, Bethesda, MD (US);
Ian A. Wilson, La Jolla, CA (US);
Natalia De Val, San Diego, CA (US);
Andrew B. Ward, San Diego, CA (US);
Dennis Burton, La Jolla, CA (US);
Linling He, San Diego, CA (US);
Jiang Zhu, San Diego, CA (US);
THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);
Abstract
The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.