Pflugerville, TX, United States of America

Lindsey C Hess


Average Co-Inventor Count = 5.5

ph-index = 1


Location History:

  • Baltimore, MD (US) (2016)
  • Pflugerville, TX (US) (2017)

Company Filing History:


Years Active: 2016-2017

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2 patents (USPTO):Explore Patents

Title: **Innovative Contributions of Lindsey C. Hess in Vitamin D Analogs**

Introduction

Lindsey C. Hess, an accomplished inventor based in Pflugerville, TX, has made significant strides in the field of pharmaceutical sciences with her innovative work on vitamin D compounds. With a total of two patents to her name, her research has the potential to revolutionize treatments for various diseases linked to abnormal cell proliferation.

Latest Patents

Hess's latest patents include groundbreaking developments in the field of vitamin D analogs. The first patent focuses on "1-deoxy analogs of 1,25-dihydroxyvitamin D3 compounds," which details novel prodrugs of activated vitamin D3. These prodrugs are designed to exhibit beneficial properties such as selective inhibition of the CYP24 enzyme, low calcemic activity, and anti-proliferative activity. Through this work, Hess aims to provide effective treatments for diseases, emphasizing the medical use of these prodrugs.

The second patent, titled "Low calcemic, highly antiproliferative analogs of calcitriol," elaborates on compounds and methods that utilize these analogs to stimulate cell differentiation and inhibit excessive cell proliferation, particularly in cancer and skin cells. This innovation is vital in treating conditions characterized by abnormal cell growth like leukemia, myelofibrosis, and psoriasis, without the adverse effects on calcium metabolism that often lead to hypercalcemia.

Career Highlights

Hess has an impressive background, having collaborated with renowned institutions such as The Johns Hopkins University and Opko Ireland Global Holdings, Limited. Her involvement in such prestigious organizations underscores her commitment to advancing medical science and improving patient outcomes.

Collaborations

Throughout her career, Lindsey C. Hess has worked alongside notable colleagues, including Gary H. Posner and Alvin S. Kalinda. These collaborations have enriched her research and contributed to the innovative solutions she has developed in her patents.

Conclusion

Lindsey C. Hess’s contributions to the field of pharmaceutical sciences, particularly through her innovative patents focused on vitamin D analogs, underline her role as a pioneering inventor. Her work promises to lead to novel therapeutic options for patients suffering from diseases driven by abnormal cell actions. As she continues to explore and expand her research, the potential impact of her inventions could greatly enhance treatment methodologies in modern medicine.

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