The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2016
Filed:
Apr. 18, 2008
Gary H. Posner, Baltimore, MD (US);
Kimberly S. Petersen, College Park, MD (US);
Lindsey C. Hess, Baltimore, MD (US);
Douglas T. Genna, Timonium, MD (US);
Scott Borella, Charlotte, NC (US);
Gary H. Posner, Baltimore, MD (US);
Kimberly S. Petersen, College Park, MD (US);
Lindsey C. Hess, Baltimore, MD (US);
Douglas T. Genna, Timonium, MD (US);
Scott Borella, Charlotte, NC (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
The disclosure provides compounds, compositions and methods using these compounds and compositions to stimulate the differentiation of cells and inhibit excessive cell proliferation of certain cells, including cancer cells and skin cells, which may be useful in the treatment of diseases characterized by abnormal cell proliferation and/or cell differentiation such as leukemia, myelofibrosis and psoriasis without the well known effect on calcium metabolism, which gives rise to hypercalcemia.