Location History:
- San Diego, CA (US) (1999)
- Denver, CO (US) (2008)
Company Filing History:
Years Active: 1999-2008
Title: Innovations of Leslie Krushel
Introduction
Leslie Krushel is a notable inventor based in Denver, CO (US). He has made significant contributions to the field of translational regulation and neural cell adhesion. With a total of 2 patents, his work has implications in both biotechnology and medical research.
Latest Patents
Krushel's latest patents include "Synthetic internal ribosome entry sites and methods of identifying same" and "Inhibition of glial cell proliferation with N-CAM homophilic peptides." The first patent focuses on synthetic and isolated translational regulatory elements, including oligonucleotides that exhibit translational enhancing activity, internal ribosome entry site (IRES) activity, or translational inhibitory activity. This patent also provides methods for using these translational regulatory elements. The second patent discloses methods and compositions useful for inhibiting glial cell proliferation by binding inhibiting agents to neural cell adhesion (N-CAM) molecules on the cell surface. These agents can include peptides derived from the homophilic binding region of N-CAM, as well as various types of antibodies.
Career Highlights
Krushel is affiliated with The Scripps Research Institute, where he has been able to further his research and innovation. His work has contributed to advancements in understanding translational regulation and its applications in medical science.
Collaborations
Some of his notable coworkers include Gerald M Edelman and Kathryn L Crossin, who have also made significant contributions to their respective fields.
Conclusion
Leslie Krushel's innovative work in translational regulation and neural cell adhesion highlights the importance of research in biotechnology and medicine. His patents reflect a commitment to advancing scientific knowledge and improving therapeutic strategies.