The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2008

Filed:

Jan. 26, 2001
Applicants:

Vincent P. Mauro, San Diego, CA (US);

Gerald M. Edelman, La Jolla, CA (US);

Stephen A. Chappell, Del Mar, CA (US);

Geoffrey Owens, San Diego, CA (US);

Jason K. Pinkstaff, Cardiff, CA (US);

Leslie Krushel, Denver, CO (US);

Wei Zhou, San Diego, CA (US);

Inventors:

Vincent P. Mauro, San Diego, CA (US);

Gerald M. Edelman, La Jolla, CA (US);

Stephen A. Chappell, Del Mar, CA (US);

Geoffrey Owens, San Diego, CA (US);

Jason K. Pinkstaff, Cardiff, CA (US);

Leslie Krushel, Denver, CO (US);

Wei Zhou, San Diego, CA (US);

Assignee:

The Scripps Research Institute, La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 15/85 (2006.01); C12N 5/10 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Synthetic and isolated translational regulatory elements, including oligonucleotides that have translational enhancing activity, internal ribosome entry site (IRES) activity, or translational inhibitory activity, and multimers of such translational regulatory elements are provided. In addition, compositions that include such translational regulatory elements are provided, as are methods of using the translational regulatory elements.


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