This inventor holds 2 USPTO granted patents and 1 EPO patent. Top assignee: Cansino Biologics Inc.. Active years: 2019-2023.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2019-2023
Title: Innovations by Lei Duan in Biologics
Introduction
Lei Duan is an accomplished inventor based in Tianjin, China. He has made significant contributions to the field of biologics, particularly in the development of cell strains and immunogenic compositions. With a total of 2 patents, his work is pivotal in advancing medical technologies.
Latest Patents
Duan's latest patents include a cell strain designed to reduce the production of replication competent adenovirus. This invention, known as HEK293.CS, is a safe adenovirus-producing cell line that enhances the stability of the E1 gene expression. Compared to the unmodified HEK293 cell strain, HEK293.CS maintains its growth and virus production capabilities while eliminating detectable replication competent adenovirus (RCA). This innovation is crucial for the mass culture of recombinant human type 5 adenovirus, particularly in the manufacturing of vaccines and antibodies.
Another notable patent is an immunogenic composition aimed at preventing pneumococcal diseases. This composition includes several components, such as PspA-MRX1 and PlyL460D, which are mixed with aluminum adjuvant for effective immunization. The formulation is designed to cover over 95% of clinically relevant strains, making it a valuable tool in pneumonia prevention. Its simple preparation method and low production cost make it suitable for large-scale industrial applications.
Career Highlights
Lei Duan is currently associated with CanSino Biologics Inc., a company known for its innovative approaches in vaccine development. His work at CanSino has positioned him as a key player in the field of biologics, contributing to advancements that have the potential to save lives.
Collaborations
Duan collaborates with notable colleagues, including Tao Zhu and Zhongqi Shao. Their combined expertise fosters an environment of innovation and progress in their research endeavors.
Conclusion
In summary, Lei Duan's contributions to the field of biologics through his patents and work at CanSino Biologics Inc. highlight his role as a significant inventor. His innovations are paving the way for advancements in vaccine development and disease prevention.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile