The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2019

Filed:

Apr. 28, 2017
Applicant:

Cansino Biologics Inc., Tianjin, CN;

Inventors:

Tao Zhu, Tianjin, CN;

Lei Duan, Tianjin, CN;

Mingming Yang, Tianjin, CN;

Zhongqi Shao, Tianjin, CN;

Xuefeng Yu, Tianjin, CN;

Helen Huihua Mao, Tianjin, CN;

Dongxu Qiu, Tianjin, CN;

Assignee:

CANSINO BIOLOGICS INC., Tianjin, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/09 (2006.01); A61K 39/116 (2006.01); A61P 31/04 (2006.01);
U.S. Cl.
CPC ...
A61K 39/092 (2013.01); A61K 39/001164 (2018.08); A61K 39/116 (2013.01); A61P 31/04 (2018.01); A61K 2039/545 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55588 (2013.01);
Abstract

The invention provides an immunogenic composition for preventing pneumococcal diseases, comprising PspA-MRX1, PspA-EF5668, PspA-EF3296 and PlyL460D, wherein the amount of each component is 10-100 μg/ml; the immunogenic composition is prepared by adding to aluminum adjuvant the corresponding dosages of the four stock solutions PspA-mRX1, PspA-EF5668, PspA-EF3296 and PlyL460D, and mixing them homogeneously; the immunogenic composition can prevent infection and invasion by, covering more than 95% of the strains in clinic. The immunogenic composition has a wide application in the prevention of pneumonia, and is suitable for large-scale production in industry for its simple preparation method, low production cost, and short production cycle.


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