Laura M Hales

Title: **Laura M. Hales: A Pioneer in Therapeutic Vitamin D Innovations**

Introduction

Laura M. Hales, based in Cambridge, MA, is an accomplished inventor with a significant contribution to the field of therapeutic vitamin D research. With a total of 11 patents to her name, Hales is making strides in enhancing the efficacy and bioavailability of vitamin D and related compounds. Her innovative work stands testament to her dedication to improving health outcomes through scientific advancements.

Latest Patents

Among her notable inventions, Hales has developed two key patents focused on therapeutic vitamin D conjugates. The first patent provides non-hormonal vitamin D conjugated to apelin proteins, which are designed to enhance absorption, bioavailability, or circulating half-life when compared to non-conjugated forms. In certain embodiments, the targeting groups of vitamin D are linked to the apelin proteins via the third carbon on the vitamin D backbone. The second patent details a parathyroid hormone (PTH) compound consisting of a PTH peptide, which demonstrates significantly increased bioavailability or circulating half-life relative to the native form of the PTH peptide. Remarkably, this PTH compound shows higher serum concentrations at multiple time points post-administration in rats compared to its native counterpart.

Career Highlights

Laura M. Hales is affiliated with Extend Biosciences, Inc., a company dedicated to advancing life science technologies. Her innovative research plays a vital role in the company's mission to develop cutting-edge therapeutic solutions. Hales' commitment to innovation in the field of biotechnology and pharmaceuticals illustrates her influence as a leader in health science.

Collaborations

Throughout her career, Hales has collaborated with several notable professionals, including her coworkers Tarik Soliman and Howard Paul Sard. These partnerships enhance the effectiveness of her research and contribute to the successful development of her patented innovations.

Conclusion

Laura M. Hales exemplifies the qualities of an innovative inventor dedicated to improving health through science. Her patented developments in therapeutic vitamin D conjugates not only reflect her expertise but also her commitment to advancing medical treatments. As she continues her work at Extend Biosciences, Inc., the future of her inventions promises to yield significant benefits in therapeutic applications.