The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2021
Filed:
Jan. 29, 2019
Applicant:
Extend Biosciences, Inc., Newton, MA (US);
Inventors:
Tarik Soliman, Cambridge, MA (US);
Laura M. Hales, Cambridge, MA (US);
Daniel B. Hall, Easton, MA (US);
Christopher So, Henderson, NV (US);
Howard P. Sard, Arlington, MA (US);
Vishnumurthy Hegde, Chelmsford, MA (US);
Assignee:
Extend Biosciences, Inc., Newton, MA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 47/60 (2017.01); A61K 47/55 (2017.01); A61K 9/00 (2006.01); A61K 38/22 (2006.01);
U.S. Cl.
CPC ...
A61K 38/10 (2013.01); A61K 9/0019 (2013.01); A61K 38/22 (2013.01); A61K 47/551 (2017.08); A61K 47/60 (2017.08);
Abstract
The invention provides a parathyroid hormone (PTH) compound comprising a PTH peptide. The PTH compound has a significantly increased bioavailability or circulating half-life when compared to a bioavailability or a circulating half-life of a native form of the PTH peptide. The PTH compound has a significantly greater serum concentration at multiple timepoints post-administration to a rat when compared to that of a native PTH peptide.