The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2017
Filed:
Oct. 21, 2015
Applicant:
Extend Biosciences, Inc., Cambridge, MA (US);
Inventors:
Tarik Soliman, Cambridge, MA (US);
Laura M. Hales, Cambridge, MA (US);
Daniel B. Hall, Easton, MA (US);
Howard Sard, Arlington, MA (US);
Vishnumurthy Hegde, Chelmsford, MA (US);
Assignee:
Extend Biosciences, Inc., Newton, MA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/28 (2006.01); A61K 9/00 (2006.01); A61K 47/48 (2006.01); C07K 14/62 (2006.01);
U.S. Cl.
CPC ...
A61K 38/28 (2013.01); A61K 9/0019 (2013.01); A61K 47/48023 (2013.01); A61K 47/48107 (2013.01); A61K 47/48215 (2013.01); A61K 47/48246 (2013.01); C07K 14/62 (2013.01);
Abstract
The invention provides non-hormonal vitamin D conjugated to insulin peptides that result in the peptides having increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. The vitamin D targeting groups are coupled to the insulin peptides via the third carbon on the vitamin D backbone.