Inventors with similar research interests:
Location History:
- Mei Foo Sun Chuen, Kowloon, CN (2015)
- Kowloon, CN (2015 - 2020)
- Mei Foo Sun Chuen, CN (2018 - 2022)
- New Territories, CN (2023)
- Hong Kong, CN (2010 - 2024)
- Shatin, CN (2019 - 2024)
- Jordan, CN (2022 - 2024)
Company Filing History:
83 out of 483 
9 out of 60 
4 out of 186 Years Active: 2010-2026
Areas of Expertise:
Title: **Kwan Chee Chan: A Pioneer in Nucleic Acid Sequence Analysis**
Introduction
Kwan Chee Chan is an esteemed inventor based in Shatin, China, with an impressive portfolio of 81 patents. His work primarily focuses on the field of molecular biology, where he has contributed significantly to advancements in cancer detection and analysis of nucleic acids.
Latest Patents
Kwan's latest patents highlight his innovative approach to identifying nucleic acid sequence imbalances that are associated with cancer. One of his notable inventions outlines methods, systems, and apparatus that enable the determination of whether a nucleic acid sequence imbalance exists within a biological sample. This patent emphasizes the use of cutoff values that can be based on the percentage of fetal DNA present in a sample, such as maternal plasma, which contains maternal nucleic acid sequences. Additionally, Kwan's work employs methods like sequential probability ratio testing (SPRT) to assess these imbalances effectively.
Another significant patent details a combined size- and count-based analysis of maternal plasma to detect fetal subchromosomal aberrations. By analyzing samples of both fetal and maternal DNA, he offers a method to classify whether an aberration—be it amplification or deletion—exists in a subchromosomal region. This dual classification approach minimizes false positives, particularly in cases where the mother has an aberration and the fetus may not.
Career Highlights
Kwan Chee Chan has had an illustrious career with significant roles in reputable institutions, notably the Chinese University of Hong Kong and Grail, Inc. His dedication and expertise have advanced the field of genetic research and cancer diagnostics, paving the way for new methodologies and applications in clinical settings.
Collaborations
Throughout his career, Kwan has collaborated with prominent figures in the field, including Rossa Wai Kwun Chiu and Yuk-Ming Dennis Lo. These partnerships have fostered a shared pursuit of knowledge and innovation, contributing to the groundbreaking developments in nucleic acid analysis and cancer research.
Conclusion
In summary, Kwan Chee Chan stands out as a transformative figure in the realm of molecular biology and cancer detection. His extensive patent portfolio and collaborative efforts underscore his commitment to advancing science and improving diagnostic methodologies. As research in this vital field continues to evolve, the contributions of innovators like Kwan will undoubtedly shape the future of healthcare and genetic analysis.