Krishnat Hanmant Kumbhar

Title: Innovations by Krishnat Hanmant Kumbhar

Introduction

Krishnat Hanmant Kumbhar is a notable inventor based in Maharashtra, India. He has made significant contributions to the field of pharmaceuticals, holding a total of 3 patents. His work focuses on improving processes for the preparation of important medicinal compounds.

Latest Patents

One of his latest patents is titled "Process for the preparation of Efinaconazole." This invention provides an improved method for synthesizing Efinaconazole in higher yields through a ring-opening addition reaction of epoxytriazole with 4-methylenepiperidine or its acid addition salt. This process is conducted under mild conditions, avoiding the need for a large excess of 4-methylenepiperidine and utilizing an alkali or an alkaline earth metal halide.

Another significant patent is "Process for preparation of darunavir and darunavir ethanolate of fine particle size." This novel process involves the reduction of a specific carbamic acid ester to produce darunavir. The invention also details the preparation of darunavir ethanolate with a particle size of less than 130 µm, 30 µm, and 10 µm.

Career Highlights

Krishnat is currently associated with Lupin, Inc., a prominent player in the pharmaceutical industry. His innovative approaches have contributed to the development of effective medications, enhancing therapeutic options for patients.

Collaborations

He has collaborated with notable coworkers such as Sachin Arun Sasane and Rajesh Harishankar Vyas, further enriching his research and development efforts.

Conclusion

Krishnat Hanmant Kumbhar's contributions to pharmaceutical innovations demonstrate his commitment to advancing medical science. His patents reflect a dedication to improving drug preparation processes, ultimately benefiting healthcare outcomes.