The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2019
Filed:
May. 10, 2016
Applicant:
Lupin Limited, Mumbai, IN;
Inventors:
Sachin Arun Sasane, Maharashtra, IN;
Devendrakumar Paramsukh Varma, Maharashtra, IN;
Rajesh Harishankar Vyas, Maharashtra, IN;
Nandu Baban Bhise, Maharashtra, IN;
Girij Pal Singh, Maharashtra, IN;
Krishnat Hanmant Kumbhar, Maharashtra, IN;
Assignee:
LUPIN LIMITED, Mumbai, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention provides an improved process for the preparation of Efinaconazole in higher yield by the ring-opening addition reaction of epoxytriazole with 4-methylenepiperidine or its acid addition salt under mild conditions without using a large excess of 4-methylenepiperidine in the presence of an alkali or an alkaline earth metal halide.