Bengaluru, India

Komal N Kanojia


 

Average Co-Inventor Count = 6.2

ph-index = 1

Forward Citations = 10(Granted Patents)


Location History:

  • Karnataka, IN (2014)
  • Bengaluru, IN (2016)

Company Filing History:


Years Active: 2014-2016

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2 patents (USPTO):Explore Patents

Title: Innovations by Komal N Kanojia

Introduction

Komal N Kanojia is a prominent inventor based in Bengaluru, India. She has made significant contributions to the field of biotechnology, particularly in the development of insulin and its analogs. With a total of two patents to her name, her work has the potential to impact diabetes treatment and protein engineering.

Latest Patents

Her latest patents include a process for expressing a fully folded functional two-chain insulin glargine. This innovative process allows for the production of insulin that requires no further processing to become functionally active. The disclosure highlights the surprising effect of overexpression of Kex2p intracellularly under the control of an inducible FLD1 promoter, enabling the production of two-chain functional glargine that is secreted directly into the medium.

Another significant patent is related to a method of reducing glycosylation of proteins, specifically insulin or insulin analog precursor molecules. This method involves genetically engineered knock-out strains of methylotrophic yeast, particularly by disrupting Protein mannosyl transferase (PMT) genes. The strains developed have been deposited at MTCC, Chandigarh, and include PMT1/GS115 (MTCC 5515), PMT4/GS115 (MTCC 5516), PMT5/GS115 (MTCC 5517), and PMT6/GS115 (MTCC 5518).

Career Highlights

Komal N Kanojia is currently employed at Biocon Limited, a leading biopharmaceutical company in India. Her work at Biocon has allowed her to focus on innovative solutions in the biotechnology sector, particularly in the development of therapeutic proteins.

Collaborations

She has collaborated with notable colleagues such as Nagaraj Govindappa and Krishnamurthy Venkatesan, contributing to a dynamic research environment that fosters innovation and advancement in biotechnology.

Conclusion

Komal N Kanojia's contributions to the field of biotechnology through her patents and work at Biocon Limited highlight her role as a significant inventor. Her innovative approaches to insulin production and protein engineering are paving the way for advancements in diabetes treatment and biopharmaceuticals.

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