Freiburg, Germany

Klaus Gubernator


Average Co-Inventor Count = 5.9

ph-index = 7

Forward Citations = 154(Granted Patents)


Company Filing History:


Years Active: 1993-2003

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15 patents (USPTO):Explore Patents

Title: Innovations of Klaus Gubernator: A Trailblazer in Thrombin-Inhibiting Compounds

Introduction

Klaus Gubernator is a renowned inventor based in Freiburg, Germany, recognized for his significant contributions to pharmaceutical innovations. With a remarkable portfolio of 15 patents, Gubernator has made a notable impact in the field of medicinal chemistry.

Latest Patents

Among his latest patents, Gubernator has developed compounds that include bicyclic and tricyclic β-lactams and guanidine derivatives. These compounds are formulated to inhibit thrombin-induced platelet aggregation and fibrinogen clotting in plasma. Specifically, the compounds described in his patents are characterized by the formula ##STR1##, where L, M, R, T, and X are determined as outlined in his patent description. These innovative compounds are synthesized through amidination or, depending on the components of the formula, amide formation or esterification, promoting innovative approaches in drug development.

Career Highlights

Klaus Gubernator's career has flourished at Hoffmann-La Roche Inc., where he has dedicated his expertise to advancing pharmaceutical research and development. His extensive work in the sector has led to breakthroughs that enhance therapeutic interventions, particularly in hematology.

Collaborations

Throughout his professional journey, Gubernator has collaborated with esteemed colleagues, including Jean Ackermann and David Banner. These partnerships have allowed for the exchange of ideas and facilitated the progression of innovative research, underscoring the importance of teamwork in achieving scientific advancements.

Conclusion

Klaus Gubernator's contributions to the field of pharmaceutical sciences exemplify the spirit of innovation that drives advancements in healthcare. His patents continue to pave the way for new therapeutic options, reflecting his commitment to improving patient outcomes and exemplifying the role of inventors in shaping future medical practices.

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